• Implicació del circuit dopaminèrgic mesolímbic i mesocortical en la motivació per reforçadors naturals i a drogues d'abús
• Neurobiologia de l’exercici físic
• Neurofarmacologia i genètica de la malaltia de Parkinson en models animals

Articles en revistes

• Mild forced exercise in young mice prevents anergia induced by dopamine depletion in late adulthood: Relation to CDNF and DARPP-32 phosphorylation patterns in nucleus accumbens Article

  Régulo Luis Olivares García, Laura López Cruz, Carla Carratalá Ros, Paula Matas Navarro, J.D. Salamone, María de las Mercedes Correa Sanz.

  NEUROPHARMACOLOGY; Vol. 262 pp. 1-12. (2025). ISSN: 0028-3908

• Effort-related motivational effects of methylphenidate: Reversal of the low-effort bias induced by tetrabenazine and enhancement of progressive ratio responding in male and female rats Article

  Alev Ecevitoglu, Renee A. Rotolo, Gayle A. Edelstein, Alexandra Goldhamer, Matthew Mitola, Rose E. Presby, Abigail Yu, Deanna Petrorazio, Emma Zorda, María de las Mercedes Correa Sanz, John D. Salamone.

  NEUROPHARMACOLOGY; Vol. 269 pp. 1-8. (2025). ISSN: 0028-3908

• The Neurobiology of Activational Aspects of Motivation: Exertion of Effort, Effort-Based Decision Making, and the Role of Dopamine Revisió

  John D. Salamone, María de las Mercedes Correa Sanz.

  ANNUAL REVIEW OF PSYCHOLOGY ; Vol. 75 pp. 1-32. (2024). ISSN: 0066-4308

• Potential therapeutics for effort-related motivational dysfunction: assessing novel atypical dopamine transport inhibitors Article

  Alev Ecevitoglu, Nicolette Meka, Renee A. Rotolo, Gayle A. Edelstein, Sonya Srinath, Kathryn R. Beard, Carla Carratalá Ros, Rose E. Presby, Jianjing Cao, Amarachi Okorom, Amy H. Newman, María de las Mercedes Correa Sanz, John D. Salamone.

  NEUROPSYCHOPHARMACOLOGY; Num. 8 Vol. 49 pp. 1309-1317. (2024). ISSN: 0893-133X

• Pharmacological characterization of sex differences in the effects of dopaminergic drugs on effort-based decision making in rats Article

  Alev Ecevitoglu, Kathryn R Beard, Sonia Srynath, Gayle A. Edelstein, Régulo Luis Olivares García, Andrea Martínez Verdú, Meka Nicolette, María de las Mercedes Correa Sanz, John D Salamone.

  PSYCHOPHARMACOLOGY ; Num. 10 Vol. 241 pp. 2033-2044. (2024). ISSN: 0033-3158

• Low-Affinity/High-Selectivity Dopamine Transport Inhibition Sufficient to Rescue Cognitive Functions in the Aging Rat Article

  Jana Lubec, Ahmed M. Hussein, Predrag Kalaba, Daniel Daba Feyissa, Edgar Andoni Arias de Saavedra Sandoval, Anita Cybulska-Klosowicz, Mekite Bezu, Tamara Stojanovic, Volker Korz, Jovana Malikovic, Nilima Y. Aher, Martin Zehl, Vladimir Dragacevic, Johann Jakob Leban, Claudia Sagheddu, Judith Wackerlig, Marco Pistis, María de las Mercedes Correa Sanz, Thierry Langer, Ernst Urban, Harald Höger, Gert Lubec.

  BIOMOLECULES; Num. 3 Vol. 13 pp. 1-17. (2023). ISSN: 2218-273X

• Effects of the atypical antipsychotic and D3/D2 dopamine partial agonist cariprazine on effort-based choice behavior: implications for modeling avolition Article

  Alev Ecevitoglu, Gayle A. Edelstein, Rose E. Presby, Renee A. Rotolo, Jen-Hau Yang, Taina Quiles, Kevin Okifo, Ryan T. Conrad, Ashley Kovach, María de las Mercedes Correa Sanz, John D. Salamone.

  PSYCHOPHARMACOLOGY ; Num. 8 Vol. 240 pp. 1747-1757. (2023). ISSN: 0033-3158

• Effort-related effects of chronic administration of the DA D-2 receptor antagonist haloperidol via subcutaneous programmable minipumps: Reversal by co-administration of the adenosine A2A antagonist istradefylline Article

  Renee A Rotolo, Alev Ecevitoglu, Rose E Presby, Hanna Lindgren, Cedric Mombereau, Cyrene Nicholas, Alana Moore, Gayle A Edelstein, María de las Mercedes Correa Sanz, John D Salamone.

  PSYCHOPHARMACOLOGY ; Num. 240 Vol. 10 pp. 2173-2185. (2023). ISSN: 0033-3158

• Sex and age differences in mice models of effort-based decision-making and anergia in depression: the role of dopamine, and cerebral-dopamine-neurotrophic-factor Article

  Paula Matas Navarro, Carla Carratalá Ros, Régulo Luis Olivares García, Andrea Martínez Verdú, John D. Salamone, María de las Mercedes Correa Sanz.

  PSYCHOPHARMACOLOGY ; Num. 11 Vol. 240 pp. 2285-2302. (2023). ISSN: 0033-3158

• Lipopolysaccharide-induced changes in effort-related motivational function: Interactions with 2-deoxyglucose Article

  Rose E. Presby, Renee A. Rotolo, Sydney Katz, Zoha Sarwat, María de las Mercedes Correa Sanz, John D. Salamone.

  PHYSIOLOGY & BEHAVIOR; Vol. 258 pp. 1-8. (2023). ISSN: 0031-9384

• Effects of the dopamine depleting agent tetrabenazine in tests evaluating different components of depressive-like behavior in mice: sex-dependent response to antidepressant drugs with SERT and DAT blocker profiles Article

  Carla Carratalá Ros, Andrea Martínez Verdú, Régulo Luis Olivares García, John D. Salamone, María de las Mercedes Correa Sanz.

  PSYCHOPHARMACOLOGY ; Num. 8 Vol. 240 pp. 1615-1628. (2023). ISSN: 0033-3158

• Critical review of RDoC approaches to the study of motivation with animal models: effort valuation/ willingness to work Revisió

  JD Salamone, María de las Mercedes Correa Sanz.

  EMERGING TOPICS IN LIFE SCIENCES; Num. 5 Vol. 6 pp. 515-528. (2022). ISSN: 2397-8554

• Efecto de la modulación dopaminérgica en la preferencia por reforzadores activos en ratones con una mutación en el factor de transcripción Pitx3 Article

  Mireia Verdejo Peñarrocha, Andrea Martínez Verdú, Régulo Luis Olivares García, Paula Matas Navarro, Carla Carratalá Ros.

  AGORA DE SALUT; Vol. VIII pp. 91-100. (2022). ISSN: 2443-9827

• Complexities and paradoxes in understanding the role of dopamine in incentive motivation and instrumental action: Exertion of effort vs. anhedonia Article

  John D. Salamone, Alev Ecevitoglu, Carla Carratalá Ros, Rose E. Presby, Gayle A. Edelstein, Reileigh Fleeher, Renee A. Rotolo, Nicolette Meka, Sonya Srinath, Jamie C. Masthay, María de las Mercedes Correa Sanz.

  BRAIN RESEARCH BULLETIN; Vol. 182 pp. 57-66. (2022). ISSN: 0361-9230

• Sex differences in lever pressing and running wheel tasks of effort-based choice behavior in rats: Suppression of high effort activity by the serotonin transport inhibitor fluoxetine Article

  Rose E. Presby, Renee A. Rotolo, Erin M. Hurley, Sarah M. Ferrigno, Cayla E. Murphy, Haley P. McMullen, Pranally A. Desai, Emma M. Zorda, Felicita B. Kuperwasser, Carla Carratalá Ros, María de las Mercedes Correa Sanz, John D. Salamone.

  PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; Vol. 202 pp. --. (2021). ISSN: 0091-3057

• Impact of Fluoxetine on Behavioral Invigoration of Appetitive and Aversively Motivated Responses: Interaction With Dopamine Depletion Article

  Carla Carratalá Ros, Laura López Cruz, Andrea Martínez Verdú, Régulo Luis Olivares García, John D. Salamone, María de las Mercedes Correa Sanz.

  FRONTIERS IN BEHAVIORAL NEUROSCIENCE; Vol. 15 pp. 1-15. (2021). ISSN: 1662-5153

• Impact of Caffeine on Ethanol-Induced Stimulation and Sensitization: Changes in ERK and DARPP-32 Phosphorylation in Nucleus Accumbens Article

  Simona Porru, Laura López Cruz, Carla Carratalá Ros, John D Salamone, Elio Acquas, María de las Mercedes Correa Sanz.

  ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH; Num. 3 Vol. 45 pp. 608-619. (2021). ISSN: 0145-6008

• Energizing effects of bupropion on effortful behaviors in mice under positive and negative test conditions: modulation of DARPP-32 phosphorylation patterns Article

  Carla Carratalá Ros, Régulo Luis Olivares García, Andrea Martínez Verdú, Edgar Arias-Sandoval, John D Salamone, María de las Mercedes Correa Sanz.

  PSYCHOPHARMACOLOGY ; Num. 12 Vol. 238 pp. 3357-3373. (2021). ISSN: 0033-3158

• The novel atypical dopamine transport inhibitor CT-005404 has pro-motivational effects in neurochemical and inflammatory models of effort-based dysfunctions related to psychopathology Article

  R.A. Rotolo, R.E. Presby, O. Tracy, S. Asar, J.H. Yang, María de las Mercedes Correa Sanz, F. Murray, J.D Salamone.

  NEUROPHARMACOLOGY; Vol. 183 pp. --. (2021). ISSN: 0028-3908

• Pharmacological studies of effort-related decision making using mouse touchscreen procedures: effects of dopamine antagonism do not resemble reinforcer devaluation by removal of food restriction Article

  Jen-Hau Yang, Rose E Presby, Adam A. Jarvie, Renee A. Rotolo, R. Holly Fitch, María de las Mercedes Correa Sanz, John D. Salamone.

  PSYCHOPHARMACOLOGY ; Num. 1 Vol. 237 pp. 33-43. (2020). ISSN: 0033-3158

• Preference for Exercise vs. More Sedentary Reinforcers: Validation of an Animal Model of Tetrabenazine-Induced Anergia Article

  Carla Carratalá Ros, Laura López Cruz, Noemí San Miguel Segura, Patricia Ibáñez Marín, Andrea Martínez Verdú, J.D Salamone, María de las Mercedes Correa Sanz.

  FRONTIERS IN BEHAVIORAL NEUROSCIENCE; Vol. 13 pp. --. (2020). ISSN: 1662-5153

• Effort-related decision making in humanized COMT mice: Effects of Val(158)Met polymorphisms and possible implications for negative symptoms in humans Article

  Jen-Hau Yang, Rose E. Presby, Suzanne Cayer, Renee A. Rotolo, Peter A. Perrino, R. Holly Fitch, María de las Mercedes Correa Sanz, Elissa J. Chesler, John D. Salamone.

  PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; Vol. 196 pp. --. (2020). ISSN: 0091-3057

• Preference for vigorous exercise versus sedentary sucrose drinking: an animal model of anergia induced by dopamine receptor antagonism Article

  María de las Mercedes Correa Sanz, Marta Pardo, Carla Carratalá Ros, Andrea Martínez Verdú, John D. Salamone.

  BEHAVIOURAL PHARMACOLOGY ; Num. 6 Vol. 31 pp. 553-564. (2020). ISSN: 0955-8810

• Effects of caffeine on ethanol-elicited place preference, place aversion and ERK phosphorylation in CD-1 mice Article

  Simona Porru, Riccardo Maccioni, Valentina Bassareo, Alessandra T. Peana, John D. Salamone, María de las Mercedes Correa Sanz, Elio Acquas.

  JOURNAL OF PSYCHOPHARMACOLOGY ; Num. 12 Vol. 34 pp. 1357-1370. (2020). ISSN: 0269-8811

• Lisdexamfetamine suppresses instrumental and consummatory behaviors supported by foods with varying degrees of palatability: Exploration of a binge-like eating model Article

  R.E Presby, , R.A Rotolo, J.-H Yang, María de las Mercedes Correa Sanz, J.D Salamone.

  PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; Vol. 189 pp. --. (2020). ISSN: 0091-3057

• The non-selective adenosine antagonist theophylline reverses the effects of dopamine antagonism on tremor, motor activity and effort-based decision-making Article

  Marta Pardo, Nicholas E. Paul, Lyndsey E. Collins-Praino, John D. Salamone, María de las Mercedes Correa Sanz.

  PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; Vol. 198 pp. --. (2020). ISSN: 0091-3057

• Behavioral and dopamine transporter binding properties of the modafinil analog (S,S)-CE-158: reversal of the motivational effects of tetrabenazine and enhancement of progressive ratio responding Article

  Renee A. Rotolo, Predrag Kalaba, Vladimir Dragacevic, Rose E Presby, Julia Neri, Emily Robertson, Jen-Hau Yang, María de las Mercedes Correa Sanz, Vasiliy Bakulev, Natalia N. Volkova, Christian Pifl, Gert Lubec, John D. Salamone .

  PSYCHOPHARMACOLOGY ; Vol. 237 pp. 3459-3470. (2020). ISSN: 0033-3158

• The dopamine depleting agent tetrabenazine alters effort-related decision making as assessed by mouse touchscreen procedures Article

  Jen-Hau Yang, Rose E. Presby, Renee A. Rotolo, Taina Quiles, Kevin Okifo, Emma Zorda, Roslyn Holly Fitch, María de las Mercedes Correa Sanz, John D. Salamone.

  PSYCHOPHARMACOLOGY ; Num. 9 Vol. 237 pp. 2845-2854. (2020). ISSN: 0033-3158

Treballs presentats en congressos publicats

• The 3 choice-T-maze task with running wheel: a mice paradigm to evaluate preference for reinforcers that require vigor and the role of dopamine in anergia

  María de las Mercedes Correa Sanz, Paula Matas Navarro, Régulo Luis Olivares García, Andrea Martínez Verdú, E. Arias Sandoval, Carla Carratalá Ros, J.D. Salamone.

  Measuring Behavior 2024. 13th International Conference on Methods and Techniques in Behavioral Research. Aberdeen (Reino Unido)

  Autoeditado por Comité congreso, 2024. ISBN: 9789074821957

• Diferencias de sexo y el efecto que produce la separación maternal. Impacto en los niveles de dopamina y la motivación por la actividad física en la edad adulta en ratones

  Paula Matas Navarro, Carla Carratalá Ros, Régulo Luis Olivares García, Andrea Martínez Verdú, María de las Mercedes Correa Sanz.

  V Congrés Investigació i Gènere a la Universitat Jaume I. Castellón (España)

  Universitat Jaume I, 2023. ISBN: 9788419647375

Tesis dirigides

• VIGOR-INDUCING EFFECTS OF DOPAMINE TRANSPORT (DAT) BLOCKERS: STUDIES USING DIFFERENT TYPES OF BEHAVIORAL ACTIVATION AND EFFORT-BASED DECISION-MAKING TASKS IN RODENTS.

  Autoria: Arias de Saavedra Sandoval, Edgar Andoni. Institució: Universitat Jaume I. Data lectura: 10/03/25

  Direcció: Correa Sanz, María de las Mercedes; Carratalá Ros, Carla

• Vulnerability to anergia in rodents: individual differences, genetic dopamine depletion and the role of the cerebral dopamine neurotrophic factor

  Autoria: Martínez Verdú, Andrea. Institució: Universitat Jaume I. Data lectura: 14/02/25

  Direcció: Correa Sanz, María de las Mercedes; Salamone, John

• Involvement of dopamine in the regulation of dysfunctions related to depression in rodent models: motivational versus emotional symptoms

  Autoria: Carratalá Ros, Carla. Institució: Universitat Jaume I. Data lectura: 25/03/20

  Direcció: Correa Sanz, María de las Mercedes; Salamone, John

• Behavioral and neurochemical assessment of the role of ERK pathway in the psychopharmacological effects of ethanol, caffeine and of their interaction

  Autoria: Porru, Simona. Institucions: Universitat Jaume I, Università degli Studi di Calgari. Data lectura: 04/02/20

  Direcció: Correa Sanz, María de las Mercedes; Elio Maria Acquas

• Screenings farmacèutics per psicofàrmacs

• Col·laboració amb el Laboratori de Neurociència Conductual del Departament de Psicologia de la Universitat de Connecticut, Estats Units.

Paraules clau

• Dopamina
• Accumbens
• Motivació
• Esforç
• Exercici
• Depressió
• Anergia
• Addicció
• Rosegadors