Universitat Jaume I

Neurofarmacología y Genética de la Conducta Motivada

Motivació, psicofarmacologia, addicció a drogues, alcohol, sistema nerviós, comportament

Codi del grup: 206

Coordinació

Correa Sanz, María de las Mercedes

Centre

FACULTAT DE CIÈNCIES DE LA SALUT

Departament

Dep. de Psicologia Bàsica, Clínica i Psicobiologia

Personal investigador en Formació	Dedicació al grup
Carratalá Ros, Carla	100 %
Olivares García, Régulo Luis	100 %

Personal col·laborador	Dedicació al grup
Ibáñez Marín, Patricia	100 %

Línies d'investigació

Implicació del circuit dopaminèrgic mesolímbic i mesocortical en la motivació a reforçadors naturals i a drogues d’abús.
Neurofarmacologia de l’addicció a l’alcohol.
Neurofarmacologia i genètica de la malaltia de Parkinson en models animals.

Serveis tecnològics i tècniques disponibles

Screenings farmacèutics per a psicofàrmacs

Codis UNESCO

(Veure detalls)

61.13.01 - ALCOHOLISMO (ver 3309.01)
61.13.02 - REACCIONES DEL COMPORTAMIENTO
61.13.03 - ABUSO DE DROGAS
61.13.04 - EFECTO DE LAS DROGAS (ver 3208.02 y 08)

Filtrar publicacions i projectes

Projectes d'investigació finançats amb fons públics

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Organisme	Codi	Títol	Inici	Fi
MINECO	PSI2015-68497-R	CORRELATOS CONDUCTUALES Y NEUROBIOLÓGICOS DE LA VULNERABILIDAD Y LA RELISENCIA A LA ANERGIA EN RATAS: APROXIMACIÓN FARMACOTERAPÉUTICA BASADA EN LAS DIFERENCIAS INDIVIDUALES	01/01/2016	31/12/2018
GV	SM I 5/2014	EJERCICIO FÍSICO PARA LA PREVENCIÓN DE LA ANERGIA EN LA DEPRESIÓN	01/01/2014	14/11/2014
UJI	P1·1A2013-01	REGULACION DOPAMINERGICA DE LAS DIFERENCIAS INDIVIDUALES EN LA ELECCION DE ACTIVIDADES QUE REQUIEREN ESFUERZO Y UN ESTILO DE VIDA ACTIVO: NEUROPROTECCION MEDIANTE EL EJERCICIO FISICO DESDE EDAD TEMPRA	01/01/2014	31/12/2016

Publicacions científiques dels membres del grup

Articles en revistes

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The monoamine-oxidase B inhibitor deprenyl increases selection of higheffort activity in rats tested on a progressive ratio/chow feeding choice procedure: Implications for treating motivational dysfunctions - Article

Samantha E. Yohn, Shanika Reynolds, Giuseppe Tripodi, María de las Mercedes Correa Sanz, John D. Salamone.

BEHAVIOURAL BRAIN RESEARCH ; 342 pp. 27-34. (2018). ISSN: 0166-4328

Neurobiology and pharmacology of activational and effort-related aspects of motivation: rodent studies - Revisió

J.D. Salamone, María de las Mercedes Correa Sanz.

CURRENT OPINION IN BEHAVIORAL SCIENCES; 22 pp. 114-120. (2018). ISSN: 2352-1546

Partial reversal of the effort-related motivational effects of tetrabenazine with the MAO-B inhibitor deprenyl (selegiline): Implications for treating motivational dysfunctions - Article

Hector Contreras-Mora , Margaret A. Rowland, Samantha E. Yohn, María de las Mercedes Correa Sanz, John D. Salamone.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; 166 pp. 13-20. (2018). ISSN: 0091-3057

Assessment of a glycine uptake inhibitor in animal models of effort-related choice behavior: implications for motivational dysfunctions - Article

Samantha E. Yohn, Daniela Alberati, María de las Mercedes Correa Sanz, John D. Salamone.

PSYCHOPHARMACOLOGY ; 9-10 pp. 1525-1534. (2017). ISSN: 0033-3158

Oral Ingestion and Intraventricular Injection of Curcumin Attenuates the Effort-Related Effects of the VMAT-2 Inhibitor Tetrabenazine: Implications for Motivational Symptoms of Depression - Article

Samantha E Yohn, Dea Gorka, Anisha Mistry, Samantha Collins, Emily Qian, María de las Mercedes Correa Sanz, Arushi Manchanda, Robin H Bogner, John Salamone.

JOURNAL OF NATURAL PRODUCTS ; 10 pp. 2839-2844. (2017). ISSN: 0163-3864

Adenosine A2A receptor deletion affects social behaviors and anxiety in mice: Involvement of anterior cingulate cortex and amygdala - Article

Laura López Cruz, María Carbó Gas, Marta Pardo Andrés, Pilar Bayarri Iturralde, Olga Valverde, Catherine Ledent, John D. Salamone, María de las Mercedes Correa Sanz.

BEHAVIOURAL BRAIN RESEARCH ; 321 pp. 8-17. (2017). ISSN: 0166-4328

Effects of lisdexamfetamine and s-citalopram, alone and in combination, on effort-related choice behavior in the rat - Article

Samantha E. Yohn, Laura López Cruz, Peter H. Hutson, María de las Mercedes Correa Sanz, John D. Salamone.

PSYCHOPHARMACOLOGY ; 6 pp. 949-960. (2016). ISSN: 0033-3158

Induction of oral tremor in mice by the acetylcholinesterase inhibitor galantamine: Reversal with adenosine A2A antagonism - Article

Podurgiel SJ , Spencer T , Kovner R , Baqi Y , Müller CE , María de las Mercedes Correa Sanz, Salamone JD .

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; 140 pp. 62-67. (2016). ISSN: 0091-3057

The pharmacology of effort-related choice behavior: Dopamine, depression, and individual differences - Article

JD. Salamone, María de las Mercedes Correa Sanz, S. Yohn, Laura López Cruz, Noemí San Miguel Segura, L. Alatorre.

BEHAVIOURAL PROCESSES ; 127 pp. 3-17. (2016). ISSN: 0376-6357

Choosing voluntary exercise over sucrose consumption depends upon dopamine transmission: effects of haloperidol in wild type and adenosine A2AKO mice - Article

María de las Mercedes Correa Sanz, Marta Pardo Andrés, Pilar Bayarri Iturralde, Laura López Cruz, Noemí San Miguel Segura, O Valverde, C Ledent, J.D. Salamone.

PSYCHOPHARMACOLOGY ; 3 pp. 393-404. (2016). ISSN: 0033-3158

Blockade of uptake for dopamine, but not norepinephrine or 5-HT, increases selection of high effort instrumental activity: Implications for treatment of effort-related motivational symptoms in psychopathology - Article

SE. Yohn, EE. Errante, A. Rosenbloom-Snow, M. Somerville, M. Rowland, K. Tokarski, N. Zafar, María de las Mercedes Correa Sanz, JD. Salamone.

NEUROPHARMACOLOGY; 109 pp. 270-280. (2016). ISSN: 0028-3908

Evaluation of the effort-related motivational effects of the novel dopamine uptake inhibitor PRX-14040 - Article

S.E. Yohn, A. Gogoj, A. Haque, Laura López Cruz, P. Huxley, P. Basquín, María de las Mercedes Correa Sanz, JD. Salamone.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; 148 pp. 84-91. (2016). ISSN: 0091-3057

Not All Antidepressants Are Created Equal: Differential Effects of Monoamine Uptake Inhibitors on Effort-Related Choice Behavior - Article

SE. Yohn, SL. Collins, HM. Contreras-Mora, EL Errante, MA. Rowland, María de las Mercedes Correa Sanz, HD. Salamone.

NEUROPSYCHOPHARMACOLOGY; 3 pp. 686-694. (2016). ISSN: 0893-133X

Effort-related motivational effects of the pro-inflammatory cytokine interleukin-6: pharmacological and neurochemical characterization - Article

SE Yohn, Y Arif, A Haley, G Tripodi, Y Baqi, CE Muller, Noemí San Miguel Segura, María de las Mercedes Correa Sanz, JD Salamone.

PSYCHOPHARMACOLOGY ; 19-20 pp. 3575-3586. (2016). ISSN: 0033-3158

Activational and effort-related aspects of motivation: neural mechanisms and implications for psychopathology - Revisió

J D. Salamone, SE. Yohn, Laura López Cruz, Noemí San Miguel Segura, María de las Mercedes Correa Sanz.

BRAIN ; 139 pp. 1325-1347. (2016). ISSN: 0006-8950

Ethanol and Caffeine Effects on Social Interaction and Recognition in Mice: Involvement of Adenosine A(2A) and A(1) Receptors - Article

Laura López Cruz, Noemí San Miguel Segura, Pilar Bayarri Iturralde, Y. Baqi, C.E. Mueller, J.D. Salamone, María de las Mercedes Correa Sanz.

FRONTIERS IN BEHAVIORAL NEUROSCIENCE; 10 pp. 1-15. (2016). ISSN: 1662-5153

The MAO-B inhibitor deprenyl reduces the oral tremor and the dopamine depletion induced by the VMAT-2 inhibitor tetrabenazine - Article

Podurgiel SJ , Yohn SE , Dortche K , María de las Mercedes Correa Sanz, Salamone JD .

BEHAVIOURAL BRAIN RESEARCH ; 298 pp. --. (2016). ISSN: 0166-4328

Neurobiological basis of motivational deficits in psychopathology - Revisió

J.D. Salamone, I. Koychev, María de las Mercedes Correa Sanz, P. McGuire.

EUROPEAN NEUROPSYCHOPHARMACOLOGY; 8 pp. 1225-1238. (2015). ISSN: 0924-977X

Selection of sucrose concentration depends on the effort required to obtain it: studies using tetrabenazine, D-1, D-2, and D-3 receptor antagonists - Article

Marta Pardo Andrés, Laura López Cruz, Noemí San Miguel Segura, J.D. Salamone, María de las Mercedes Correa Sanz.

PSYCHOPHARMACOLOGY ; 13 pp. 2377-2391. (2015). ISSN: 0033-3158

The VMAT-2 inhibitor tetrabenazine alters effort-related decision making as measured by the T-maze barrier choice task: reversal with the adenosine A(2A) antagonist MSX-3 and the catecholamine uptake - Article

S.E. Yohn, C. Thompson, P.A. Randall, C.A. Lee, C.E. Müller, Y. Baqi, María de las Mercedes Correa Sanz, J.D. Salamone.

PSYCHOPHARMACOLOGY ; 7 pp. 1313-1323. (2015). ISSN: 0033-3158

The role of dopamine D1 receptor transmission in effort-related choice behavior: Effects of D1 agonists - Article

S.E. Yohn, J.L. Santerre, E.J. Nunes, R. Kozak, S.J. Podurgiel, María de las Mercedes Correa Sanz, J.D. Salamone.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR; 135 pp. 217-226. (2015). ISSN: 0091-3057

Fluoxetine Administration Exacerbates Oral Tremor and Striatal Dopamine Depletion in a Rodent Pharmacological Model of Parkinsonism - Article

S.J. Podurgiel, M. Milligan, S.E. Yohn, L. Purcell, H.M.M. Contreras, María de las Mercedes Correa Sanz, J.D. Salamone.

NEUROPSYCHOPHARMACOLOGY; 9 pp. 2240-2247. (2015). ISSN: 0893-133X

Bupropion Increases Selection of High Effort Activity in Rats Tested on a Progressive Ratio/Chow Feeding Choice Procedure: Implications for Treatment of Effort-Related Motivational Symptoms - Article

P.A. Randall, C.A. Lee, S.J. Podurgiel, E.E. Hart, M. Jones, M. Rowland, Laura López Cruz, María de las Mercedes Correa Sanz, J.D. Salamone.

INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY; 2 pp. 1-11. (2015). ISSN: 1461-1457

The VMAT-2 Inhibitor Tetrabenazine Affects Effort-Related Decision Making in a Progressive Ratio/Chow Feeding Choice Task: Reversal with Antidepressant Drugs - Article

P.A. Randall, C.A. Lee, E.J. Nunes, S.E. Yohn, V. Nowak, B. Khan, P. Shah, S. Pandit, V.V. Kiran, A. Makriyannis, Y. Baqi, C.E. Müller, María de las Mercedes Correa Sanz, J.D. Salamone.

PLOS ONE; 6 (9) Article number e99320 pp. 1-17. (2014). ISSN: 1932-6203

Effort-related motivational effects of the pro-inflammatory cytokine interleukin 1-beta: studies with the concurrent fixed ratio 5/ chow feeding choice task - Article

E.J. Nunes, P.A. Randall, A. Estrada, B. Epling, E.E. Hart, C.A. Lee, Y. Baqi, C.E. Müller, María de las Mercedes Correa Sanz, J.D. Salamone.

PSYCHOPHARMACOLOGY ; 4 pp. 727-736. (2014). ISSN: 0033-3158

Differences between the nonselective adenosine receptor antagonists caffeine and theophylline in motor and mood effects: Studies using medium to high doses in animal models - Article

Laura López Cruz, Marta Pardo Andrés, J.D. Salamone, María de las Mercedes Correa Sanz.

BEHAVIOURAL BRAIN RESEARCH ; 270 pp. 213-222. (2014). ISSN: 0166-4328

Conditional neural knockout of the adenosine A2A receptor and pharmacological A2A antagonism reduce pilocarpine-induced tremulous jaw movements: Studies with a mouse model of parkinsonian tremor - Article

J.D. Salamone, L.E.C. Praino, Marta Pardo Andrés, S.J. Podurgiel, Y. Baqi, C.E. Müller, M.A. Schwarzschild, María de las Mercedes Correa Sanz.

EUROPEAN NEUROPSYCHOPHARMACOLOGY; 8 pp. 972-977. (2013). ISSN: 0924-977X

The vesicular monoamine transporter (VMAT-2) inhibitor tetrabenazine induces tremulous jaw movements in rodents: Implications for pharmacological models of parkinsonian tremor - Article

S.J. Podurgiel, E.J. Nunes, S.E. Yohn, J. Barber, A. Thompson, M. Milligan, C.A. Lee, Laura López Cruz, Marta Pardo Andrés, O. Valverde, C. Lendent, Y. Baqi, C.E. Müller, María de las Mercedes Correa Sanz, J.D. Salamone.

NEUROSCIENCE; 250 pp. 507-519. (2013). ISSN: 0306-4522

Dopamine and food addiction: lexicon badly needed - Revisió

J.D. Salamone, María de las Mercedes Correa Sanz.

BIOLOGICAL PSYCHIATRY; 73 pp. 15-24. (2013). ISSN: 0006-3223

C-Fos immunoreactivity in prefrontal, basal ganglia and limbic areas of the rat brain after central and peripheral administration of ethanol and its metabolite acetaldehyde - Article

K.N. Segovia, R. Vontell, Laura López Cruz, J.D. Salamone, María de las Mercedes Correa Sanz.

FRONTIERS IN BEHAVIORAL NEUROSCIENCE; (7) Article Number: 48 pp. 1-11. (2013). ISSN: 1662-5153

Insulin and Ventral Tegmental Dopamine: What's Impaired and What's Intact? - Article

J Salamone, María de las Mercedes Correa Sanz.

CELL METABOLISM; 17 pp. 469-470. (2013). ISSN: 1550-4131

Acetate as an active metabolite of ethanol: studies of locomotion, loss of righting reflex, and anxiety in rodents - Article

Marta Pardo Andrés, A.J. Betz, Noemí San Miguel Segura, Laura López Cruz, J.D. Salamone, María de las Mercedes Correa Sanz.

FRONTIERS IN BEHAVIORAL NEUROSCIENCE; Article Number: 81 pp. 1-10. (2013). ISSN: 1662-5153

Nucleus accumbens neurotransmission and effort-related choice behavior in food motivation: effects of drugs acting on dopamine, adenosine, and muscarinic acetylcholine receptors - Article

E.J. Nunes, P.A. Randall, S.J. Podurgiel, María de las Mercedes Correa Sanz, J.D. Salamone.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS; 9 pp. 2015-2025. (2013). ISSN: 0149-7634

La dopamina regula la motivación - Article

María de las Mercedes Correa Sanz, J.D. Salamone.

MENTE Y CEREBRO; 62 pp. 45-47. (2013). ISSN: 1695-0887

Effort-Related Motivational Effects of the VMAT-2 Inhibitor Tetrabenazine: Implications for Animal Models of the Motivational Symptoms of Depression - Article

E.J. Nunes, P.A. Randall, E.E. Hart, C. Freeland, S.E. Yohn, Y. Baqi, C.E. Müller, Laura López Cruz, María de las Mercedes Correa Sanz, J.D. Salamone.

JOURNAL OF NEUROSCIENCE; 49 pp. 19120-19130. (2013). ISSN: 0270-6474

Effect of subtype-selective adenosine receptor antagonists on basal or haloperidol-regulated striatal function: Studies of exploratory locomotion and c-Fos immunoreactivity in outbred and A(2A)R KO mi - Article

Marta Pardo Andrés, Laura López Cruz, O. Valverde, C. Ledent, Y. Baqi, C.E. Müller, J.D. Salamone, María de las Mercedes Correa Sanz.

BEHAVIOURAL BRAIN RESEARCH ; 247 pp. 217-226. (2013). ISSN: 0166-4328

The Impact of Caffeine on the Behavioral Effects of Ethanol Related to Abuse and Addiction: A Review of Animal Studies - Revisió

Laura López Cruz, J.D. Salamone, María de las Mercedes Correa Sanz.

JOURNAL OF CAFFEINE RESEARCH; 1 pp. --. (2013). ISSN: 2156-5783

Capítols de llibres

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Neurobiology of Effort and the Role of Mesolimbic Dopamine

John D. Salamone, María de las Mercedes Correa Sanz.

Recent Developments in Neuroscience Research on Human Motivation. Emerald, Bingley (Reino Unido). (2017). ISBN: 9781786354747

Motor function and motivation

John D. Salamone, María de las Mercedes Correa Sanz.

Reference Module in Neuroscience and Biobehavioral Psychology. Elsevier, Amsterdam (Paises Bajos). (2017). ISBN: 9780128093245

Mesolimbic Dopamine and the Regulation of Motivated Behavior

J.D Salamone, Marta Pardo Andrés, S.E Yohn, Laura López Cruz, Noemí San Miguel Segura, María de las Mercedes Correa Sanz.

Behavioral Neuroscience of Motivation. Springer, (756) (Suiza). (2016). ISBN: 9783319269337

Section V: Chapter 38: Physiological and Behavioral Assessment of Tremor in Rodents

J.D Salamone, S.J Podurgiel, L.E Collins-Praino, María de las Mercedes Correa Sanz.

Movement Disorders: Genetics and Models. Elsevier, Amsterdam (Paises Bajos). (2015). ISBN: 9780124051959

Dopamine/adenosine interactions related to tremor in animal models of Parkinsonism.

J.D Salamone, S Podurgiel, L.L Long, E.J Nunes, María de las Mercedes Correa Sanz.

The Adenosinergic System: A non-dopaminergic target in Parkinson's Disease. Springer, (756) (Suiza). (2015). ISBN: 9783319202723

The role of adenosine in the ventral striatal circuits regulating behavioral activation and effort-related decision making: Importance for normal and pathological aspects of motivation

J.D. Salamone, María de las Mercedes Correa Sanz, P.A. Randall, E.J. Nunes, Marta Pardo Andrés, Laura López Cruz.

Adenosine: a Key Link between Metabolism and Brain Activity. Springer, New York (Estados Unidos de América). (2013). ISBN: 9781461439028

Treballs presentats en congressos publicats

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Caffeine induces anxiety and impairs social interaction in mice: the role of adenosine receptors and impact on ethanol (Abstract)

Laura López Cruz, Noemí San Miguel Segura, María Carbó Gas, P. Bayarri, Marta Pardo Andrés, X. Ros, O. Valverde, C. Ledent, J.D. Salamone, María de las Mercedes Correa Sanz.

15th Biennial Meeting of the European Behavioural Pharmacology Society (EBPS 2013). La Rochelle (Francia)

2013. ISSN: 0955-8810

Altres dades

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Col·laboració amb el Laboratori de Neurociència Conductual del Departament de Psicologia de la Universitat de Connecticut, Estats Units, dirigit pel Dr. J.D. Salamone.

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